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Lab report showing Liver Function Test results with blood sample tube

LFT Test Explained — Complete Liver Function Test Guide

TL;DR — Key Takeaways
  • LFT checks the liver's health and function
  • ALT (SGPT) and AST (SGOT) are the most common markers
  • High values can indicate liver damage, hepatitis, or fatty liver
  • Fasting is sometimes required — follow your doctor's instructions
  • LFT is also common in routine checkups and medication monitoring
LFT Test — Quick Facts
Full formLiver Function Test
Main markersALT (SGPT), AST (SGOT), Bilirubin, Alkaline Phosphatase
SampleBlood test (venous)
FastingRequired in some cases, your doctor will confirm
Common usesHepatitis screening, fatty liver, medication monitoring

What Is an LFT Test?

LFT (Liver Function Test) is a group of blood tests that assess the liver's health and function. The liver is one of the body's most important organs — it clears toxins, produces proteins, and aids digestion. LFT helps detect early signs of liver damage or disease.

What Does LFT Check?

  • ALT (SGPT) — a liver cell enzyme that leaks into the blood when cells are damaged
  • AST (SGOT) — an enzyme found in both liver and muscle tissue
  • Bilirubin — a byproduct of RBC breakdown; high levels cause jaundice
  • Alkaline Phosphatase (ALP) — an indicator of bile duct problems
  • Albumin — a protein made by the liver; a measure of liver function
  • Total Protein — overall liver synthesis function

Normal Ranges (Approximate)

MarkerNormal Range
ALT (SGPT)7-56 U/L
AST (SGOT)10-40 U/L
Total Bilirubin0.1-1.2 mg/dL
Albumin3.5-5.0 g/dL

Note: Reference ranges may vary slightly by lab — check the range printed on your own report.

When Is LFT Ordered?

  • Routine health checkup
  • Hepatitis screening (Hepatitis B and C are common in Pakistan)
  • Fatty liver monitoring
  • For those on long-term medications — like TB medicines, statins
  • Signs of jaundice — yellow skin/eyes
  • History of alcohol consumption
  • Unexplained fatigue or abdominal pain

What Abnormal Results Mean

  • High ALT/AST — liver cell damage (hepatitis, fatty liver, medication effect)
  • High Bilirubin — jaundice, bile duct blockage, or hemolysis
  • Low Albumin — chronic liver disease or poor nutrition
  • High ALP — bile duct problem or bone disease

Is a value on your LFT report coming back high? Discuss your report with a doctor on Ilaaj AI and learn next steps.

Discuss Your Report with a Doctor

Preparing for LFT

Some cases require 8-12 hours of fasting, especially if a lipid profile is ordered alongside it. Confirm with your doctor or lab whether fasting is needed.

When to See a Doctor

  • Any LFT value is abnormal
  • Yellowing of skin or eyes
  • Persistent fatigue, right-sided abdominal pain
  • Long-term alcohol or medication use

Conclusion

The LFT test is an essential window into liver health — helping detect everything from hepatitis to fatty liver. Don't ignore abnormal results — discuss your report with a doctor on Ilaaj AI and learn the right next steps.

Frequently Asked Questions

Is fasting required for an LFT test?

Sometimes, especially if a lipid profile is ordered alongside it. Confirm with your doctor or lab — a general LFT often doesn't require fasting, but each lab may have its own policy.

What does high ALT or AST mean?

High values indicate liver cell damage — this could be from hepatitis, fatty liver, alcohol effects, or certain medications. Your doctor may recommend further tests (like hepatitis screening or an ultrasound).

How often should I get an LFT?

Yearly is enough for a routine checkup if there are no risk factors. Those on long-term medications (TB medicines, statins) may need more frequent testing (like every 3 months) as advised by their doctor.

Can Hepatitis B or C be detected by LFT?

LFT itself doesn't diagnose hepatitis, but abnormal liver enzymes prompt doctors to order specific hepatitis screening tests (HBsAg, Anti-HCV).

What does high bilirubin on LFT mean?

High bilirubin causes jaundice (yellow skin/eyes) — it can be caused by liver disease, bile duct blockage, or RBC breakdown (hemolysis). See a doctor for further evaluation.

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